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Instead of being released by the presynaptic neuron, endocannabinoids are released by the postsynaptic neuron, whereupon they travel across the synapse in the opposite direction from most transmitters and bind to CB receptors on the presynaptic neuron (see image below)

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In addition to its 2010 Supreme Court case that barred states from banning lawful gun ownership, it has helped successfully challenge assault weapons bans, magazine-capacity limits, and age restrictions on handgun sales

Archived from the original on July 20, 2016
