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Airflow: The airflow and ease of draw dont directly affect the nicotine content

(2020) levels of SCFAs are reduced by the peripheral -opioid receptor agonist and anti-diarrheal agent loperamide, perhaps due to a decrease in butyrate-producing bacteria (Touw et al

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Moreover, modeling under a wide range of assumptions suggests that the availability of ENDS saves life-years overall, even under unrealistically pessimistic assumptions (Warner & Mendez, 2019)

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