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Therefore, it is plausible that the increased susceptibility to disease progression and the subsequent fatal outcome in this population is related to poor angiotensin 1-7 (Ang-1-7) generation, the main peptide generated by ACE2, and probably to their inaccessibility to its anti-inflammatory effects

Dry eye syndrome: Dry eye syndrome is an eye condition that can be aggravated or caused by smoking, leading to red, irritated and gritty eyes

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Methods Information on all births in Norway has routinely been collected by the Medical Birth Registry of Norway since 1967 [11]