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These indirectly trigger reward circuitry, and though they can still cause addiction, tend not to have a physical dependency, and therefore dont have the serious withdrawals associated with physical addictions

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Weiland, B

Reference Eerkens, Ardura, Fiehn, Blake, Lentz, Tushingham and Palazoglu2012

The results show American Spirit smokers had a higher exposure to nicotine per cigarette smoked compared with other brands, which suggested a greater addictive potential. American Spirit ads convey the cigarettes as less harmful and non-addictive Are American Spirit Cigarette ads allowed to say they are less harmful

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