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As the demand increased the profits became correspondingly great, and every other species of labor was abandoned for the cultivation of tobacco

The FDA outlines exactly what you need for your Substantial Equivalence Report, but figuring out if your product qualifies requires a deep dive into the regulations

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It means giving up the cozy comfort of that hand-to-mouth habit and the oh-so-satisfying drag of a cigarette

The packs used in the FGDs were bought in Mexico City shortly before the sessions to reflect products on the market at the time