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To reduce the effect of bias, we adjusted observations that did not account for more than five confounders, including age and sex, because they were the significant bias covariates identified by the bias covariate selection algorithm 29 (Supplementary Table 7)

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In controlled clinical trials, NRT increases smoking cessation rates at 1-year follow-up by approximately 5060% over placebo [11], but its real-world effectiveness is lower [12, 13]

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The Salt ingredient (e.g Lactic Acid, Benzoic Acid) is added to nicotine vaping products to allow higher concentrations of nicotine to be vaped without a nasty throat hit