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Description
Semaglutide activates GLP-1 receptors in the hypothalamus the part of the brain that regulates hunger and satiety

That is roughly 33 pounds for someone starting at 220 pounds

The GLP-1 agonists currently available require daily or weekly subcutaneous injection
Neither medication has received Health Canada approval as of late 2025
NCT03693430

The weight loss dosage chart provides guidance by weight range
