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There are many pediatric-specific considerations (ie, available pediatric-trained personnel, multiplace chambers, the need for myringotomy) in HBO therapy, and early consultation is recommended to ensure the proper considerations, equipment, and personnel are in place to not delay HBO therapy

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In this context, it is widely accepted that platelet and leukocyte activation as well as endothelial dysfunction are associated with atherogenesis and cardiovascular morbidity [18, 19]