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This explains why the digestive effects of smoke-free nicotine products like ZYN can differ from cigarettes
In the oral cavity, smoking-induced dysbiosis plays a significant role in the development of oral diseases, such as periodontitis, by disrupting the balance of oral microbiota and promoting pathogenic species that drive inflammation and tissue destruction [13, 14]
2, 5 In addition, the red blood cells become filled with carboxyhemoglobin, which further diminishes tissue oxygenation
It is deemed "generally safe" by the FDA, but inhaling PG in excess can be a cause for concern
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