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A person may spread themselves too thin, ending up totally exhausted

The new study, Handa says, shows smoking also causes epigenetic changesnon-permanent shifts in gene expression that are not caused by changes in a cells DNA sequenceto retinal pigmented epithelial cells, or RPE cells, that have widespread effects on the eye and its ability to respond to environmental stress

never smoking as a significant risk factor (hazard ratio, 1.26

PLoS ONE, 11 (5), Article e0154447

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