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In iPSC-EC exposed to e-liquids, evidence of endothelial dysfunction were observed including lower cell viability, higher production of IL-1 and 6, ROS production, activation of OS-related pathway, caspase 3/7 activity, low-density lipoprotein uptake (LDL), and disrupted tube formation and migration [31]

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Critically, our findings are not meant to detract from the substantive cancer risks associated with smoking which remains the single largest preventable cause of cancer worldwide [54], and for which even very low levels of exposure are associated with an increased risk of cancer [46]

[DOI] [PubMed] [Google Scholar] 230.Soler P., Moreau A., Basset F., Hance A.J

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How to Remove Smoking Stains From Teeth at Home: Evidence-Based Strategies Professional treatment produces the most dramatic results, but a strong home care routine is essential for maintaining your investment and managing ongoing staining between visits