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PCA indicated that the metabolomic profiles clustered by both smoking status and bacterial community state type (CST) (Figure S1)

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The percentages of cells in blood were determined on BD FACS Calibur (Becton Dickinson) and data were analyzed with FlowJo software (Tree Star, Inc.)

Chewing sugar-free gum or healthy snacking : Keeping your mouth busy can help satisfy the mouth urges that often come with nicotine cravings

According to a recent Gallup poll, the percentage of Americans 18-34 who say they drink at all dropped 10% over the past 2 decades

The Camel campaign was hardly the first, nor the last, to prominently feature doctors endorsing tobacco use