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Martinus Beijerinck, while repeating Ivanowskis experiments, recognized that he was dealing with a pathogen of a novel type, much smaller than a bacterium, which he called virus in 1898 to indicate its non-bacterial nature [20-22]

Current projections estimate that by 2020, COPD will be the third leading cause of death worldwide, behind heart disease and cancer, and the fifth leading cause of years lost through early mortality or disability [ 50 , 51 ]

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However, most recently the FDA, in its latest crackdown on e-cigarettes, said that it "won't tolerate a whole generation of young people becoming addicted to nicotine as a trade-off for enabling adults to have unfettered access to these same products." This suggests that the FDA doesn't just see its role as waging an all-out war to kill traditional tobacco products in the U.S., but is outright trying to eliminate nicotine addiction entirely