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This Comment highlights emerging evidence and advocates for clinical strategies that prioritize muscle preservation to ensure the long-term success and safety of pharmacological weight management

Frontline Gastroenterol 2014

This review was not registered with PROSPERO or any other database

Anti-sympathetic drugs, such as -blockers, may represent suitable candidates in combination with DPP-4 for the treatment of hypertension with which to prevent sympathetic activity

All data are preliminary and may change as additional data are obtained

Trends in first-time prescribing First-time prescribing rates (first-time GLP-1 RA prescriptions per total prescriptions) in December 2025 decreased, relative to September 2025 (-6.6%)