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Pharmacologic Implications DPP-4 inhibitors comprise a class of non-insulin anti-diabetic therapeutic interventions that enhance insulin secretion by pancreatic -cells and act by blocking the enzymatic action of DPP-4

In this context, recent EULAR Points to Consider emphasize the importance of recognizing clinical and imaging features suggestive of progression from PsO to PsA, including arthralgia, enthesitis, subclinical synovitis on ultrasound or MRI, and elevated inflammatory markers (12)

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It is a hormone the body already produces, provided the right signals are present