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The balance between genotoxins and benign metabolites is presumed to depend on concentration, localization, pH and redox state, features that are or potentially altered during disease progression ( 4 Pathway changes associated with cellular damage and inflammation in brain A systematic review of the effects of active and passive smoking of conventional cigarettes, electronic cigarettes and tobacco heating products indicated that active and passive smoking induce oxidative stress and inflammatory responses in peripheral tissues (Kopa-Stojak and Pawliczak, 2024

Karlee Adams, Tobacco Prevention and Control Program manager, echoed Karzen in a prepared statement, saying even though more research is needed," it's already clear that using nicotine can "damage the developing brain." "We look forward to collaborating with other agencies to develop policies to protect our youth

Todays research shows that the more we can stop smoking uptake and support people to quit, the less they will end up needing the support of the Australian health system, Mr Harper concluded