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Hoffmann, D
This risk is especially high for countries with strict tobacco import laws
Data published in October 2025 suggest that an estimated 1.6% of adults in England used oral nicotine pouches, equating to around 777,000 people, while 14.2% used vapes and 15% smoked cigarettes 3,4
Given that smoking is one of the leading risk factors for disease burden and premature death, these differences matter a lot for public health
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Once the Food and Drug Administration verifies a drug's safety, clinical trials would begin to see how it works in a human.
