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n = 81) reported that the withdrawal symptoms started in less than 6 h since their last e-cig use, while 15.5% (n = 81) started to feel the withdrawal symptoms after more than 16 h

Healthcare providers, local Stop Smoking Services, and resources such as the NHS Smokefree Helpline (free to call 0300 123 1044 and available in England) can offer valuable assistance

If you hear four beeps, you know that a signal was sent to your monitoring station

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Details on each, including the studys design, data sources, number of participants, length of follow-up, confounders adjusted for in the input data and bias covariates included in the doseresponse risk model, can be found in Supplementary Information 2 and 3