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The protein expression of Akt, STAT3, Erk, EMT, and MMP-9 on A549 cells was evaluated by Western blotting after harmine treatment with doses of 0 (served as negative control), 10, and 20 M exhibiting a substantial reduction in STAT3, Akt, Erk, and MMP-9 expression (Shen et al

Cigarettes are ventilated due to air permeability of cigarette paper and through these holes on the rim of the filter

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Among other substances, the following were identified: Carbon monoxide Ammonia Acetaldehyde Formaldehyde Phenols Nitrosamine Hydrocarbons Many of these components are carcinogenic and harmful to the respiratory epithelium, such that smoking marijuana is associated with airway inflammation, although greater damage has been documented in smokers who smoked tobacco in addition to cannabis

Lancet 340(8828):11111115 Celermajer DS et al (1993) Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults

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