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Vijayaraghavan, W

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People have been fascinated and perplexed by these involuntary diaphragmatic contractions, which are accompanied by a characteristic hic sound, for generations
Specifically, given the known acute effect of 4-HNE in activating uncoupling proteins to lower mitochondrial membrane potential, the lower abundance of ANT and UCP3 observed after 8 mo of cigarette smoke exposure might represent a late adaptation to restore proton leak when the mitochondrial membrane potential has reached a critical value that may compromise the rate of ATP synthesis

Psychiatry 41 , 416425 (2000)

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