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This can make smoking less convenient, especially in public places where smoking is restricted

While their overall market share is smaller, their cultural importance ensures continued relevance within the industry

Nicotine patches and gum are not the same as taking a drag on a cigarette, says Bhatnagar

& Kanhere, S

1 Introduction Cigarette smoking has a negative effect on health, resulting in massive health-related economic losses that include substantial morbidity and mortality ( Nicotine dependence can be defined as a pattern of psychological attributes that result in the compulsive and repetitive search for, and use of, nicotine ( Astrocytes are glial cells that regulate the cellular absorption and release of glutamate, e.g., glutamate homeostasis, thereby affecting the development of drug dependence ( xCT is an antiporter, reliant on L-cysteine, that also contributes to glutamate homeostasis

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