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This occurs largely through a metabolic adaptation to higher levels of chronic oxidative stress, resulting in an enhanced reductive state (higher levels of reducing equivalents) able to reset overall redox homeostasis

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But research tells a very different story: The vents in the filter change the way the tobacco burns, creating more toxins and cancer-causing substances

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The researchers found that epithelial cells (cells that typically line organs and are often the cells of origin for cancer) in the mouth showed substantial epigenomic changes in smokers

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