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These include how often and how much tobacco they consume, biochemical markers (such as levels of cotinine, a by-product of nicotine metabolism) (covered in 12.5.6 Biomarkers of tobacco smoke and damage), and self-reported smoking behaviour measured in questionnaires

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Longitudinal studies integrating metagenomic, transcriptomic, metabolomic, methods with clinical results may help us ascertain the relationships between smoking, microbiome, and pathological mechanism in diseases

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Archived from the original on November 4, 2023