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Finally, we showed that pharmacological inhibition of the thioredoxin system by the chemotherapeutic drug arsenic trioxide (ATO) enhanced MTX cytotoxicity in vivo against one out of four primary human ALL cells, suggesting a novel therapeutic rationale to be further explored against ALL
Hodges H, Fealko C, Soares N

These protect mitochondrial integrity under stress conditions, reducing oxidative damage that would otherwise slow or prevent healing

Novitskaya, L., Trevanion, S
Soluble TNF-alpha receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight