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The first few puffs tend to cook off quite a bit of the Latakia, and that gives the smoke a real kick of the signature campfire-esque nature celebrated by those who are a fan of the genre

Once inside, Sean will continue his buddy-buddy act with Hamish

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1 H NMR (500 MHz, DMSO) 13.10 (s, 1H), 8.15 (dd, J = 9, 5.5 Hz, 2H), 7.92 (dd, J = 7.9, 1.5 Hz, 1H), 7.617.58 (m, 1H), 7.40 (t, J = 8.5 Hz, 2H), 7.35 (dd, J = 8,5, 7.0 Hz, 2H), 5.88 (s, 1H), 5.86 (d, J = 5.0 Hz, 1H), 4.284.23 (m, 3H), 3.60 (dd, J = 18.0, 4.5 Hz, 1H), 3.463.42 (m, 1H)

Therefore, we separated our analysis of HRV and morphology parameters into 4 discrete phasesBaseline (BL), mid-exposure (Expo, all min of puff sessions), early after exposure (Post-, 49 min after each puff session), and late after exposure (Late Post-, 928 min after final puff session)