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Crohn's disease is an inflammatory intestinal condition which creates pain and irritation in the GI tract

Table 1 By the end of week 1 before CRS guidance, 33% (28/85) (95% CI: 23.144.0) of participants showed no reduction in cigarette consumption, while 8% (7/85) (95% CI: 3.416.0) reported mild, 43% (37/85) (95% CI: 3355) moderate, and 15% (13/85) (95% CI: 825) significant reduction

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The realistic feel and design help to satisfy the psychological hand-to-mouth habit that many smokers find hard to break