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Description
Tolerance (A process in which the body needs more and more of a drug to get the same effect.) When the body experiences craving as the nicotine disappears or is absent then that is a sign of physical dependence(A type of addiction in which the body itself feels a direct need for a drug)

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Because CBD is the active ingredient in an FDA-approved drug, the FDA is responsible for regulating its sale in the U.S

Mecamylamine has been shown to block many of the physiological, behavioral, and reinforcing effects of nicotine (Collins et al., 1986

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