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Description
NF - B inhibition prevents CS-induced upregulation of MuRF1 and CS-induced reduction in the diameter and degradation of the MyHC -related C2 myotubes [2], suggesting that inflammation is responsible for CS-induced proteasomal degradation in skeletal muscle
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A similar study from Ranxu Zhu et al
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A protective activity of nicotinamide has also been linked to the regulation of p53 and sirtuins in vitro [114] and in NMSC cases under clinical trials [115]
