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The decision to write down the value of some of its brands was a bold step for BAT because despite the short-term pain, the reality is that the market for cigarettes is shrinking, and pretending otherwise would be irresponsible on the part of management, he says

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1, but not the regulation limiting where adults can and cannot use them

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In one study, oral nicotine administered to rats to achieve blood levels comparable to those in human smokers produced myointimal thickening of the aorta after an experimental injury (denudation of the endothelium with a balloon catheter) (Krupski et al

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