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Non-combusted products - such as e-cigarettes and other smokeless tobacco products - generally have lower health risks than cigarettes and other combustible tobacco products

doi:10.2196/jmir.1100Google Scholar Quinn, C

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Moreover, there is currently insufficient strong evidence to establish the association between pharmacological treatments and adverse events

According to Foulds, the evidence that nicotine is harmful to the developing brain is of about the same quality as evidence on the impact of caffeine on young people