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Acutely increasing the tonic activity of VTA DA neurons using optogenetics is sufficient to mimic the behavioral bias (decreased exploration) induced by nicotine, suggesting that the DA control of the exploration/exploitation balance is altered by long-term nicotine exposure

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Linked to this, encouraging findings from the National Health and Nutrition Examination Survey (NHANES) show the percent of non-smokers exposed to SHS decreased from 88% in 1988 to 25% in 2014, but around two of every five children were still exposed to the harmful effects of SHS

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10.1152/ajplung.00411.2014 [DOI] [PMC free article] [PubMed] [Google Scholar] Sharentuya N, Tomimatsu T, Mimura K, Tskitishvili E, Kinugasa-Taniguchi Y, Kanagawa T, Kimura T, 2010