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Smokers are more likely to develop chronic bronchitis, pneumonia, and tuberculosis (TB)

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Carpenter worries about the possibility of addiction because the devices are promoted as being safer than conventional cigarettes

Because the addictive nature of nicotine is not uniform across all people, NIH estimates that as little as 0.5 mg of nicotine may be required to make cigarettes nonaddictive, perhaps even less, if the agency decides to include children in the study because they haven't built up a tolerance to nicotine yet