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Also, mouse studies reported here show that BMD increases within a short period after nicotine discontinuation accompanied by significantly reduced serum levels of TRAP5b, a marker of bone resorption

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Mauries, S., Bertrand, L., Frija-Masson, J., Benzaquen, H., Kalamarides, S., Sauvage, K., Lejoyeux, M., DOrtho, M., & Geoffroy, P

This makes them a practical tool for smokers who want to stop smoking without feeling deprived