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Although this supports the biological plausibility of tissue injury and disease from long-term exposure to e-cigarette aerosols, generation of reactive oxygen species and oxidative stress induction is generally lower from e-cigarettes than from combustible tobacco cigarette smoke

Cigarette smoking is a risk factor for Alzheimer's Disease: an analysis controlling for tobacco industry affiliation

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4.3 Histopathological Findings Histopathology can also be used as a diagnostic tool to confirm the diagnosis of PR in atypical cases and help differentiate PR from other similar-looking conditions

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[8] His father was emotionally distant and constantly belittled him