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Inactivation of specific beta cell transcription factors in type 2 diabetes

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All three doses of orforglipron (6 mg, 12 mg, and 36 mg) studied in that trial met the primary and all key secondary endpoints by showing significant weight loss, meaningful A1C reductions, and improvements in cardiometabolic risk factors compared with placebo at 72 weeks

[DOI] [PubMed] [Google Scholar] 113.Boysen NC, Stone MS

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With widespread consumer advertising campaigns, GLP-1 usage is becoming commonplace