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Key Takeaway In HIV-positive patients, the virus causes chronic inflammation, which leads to an increase in disease rates

C., Ouimet, J., Quah, A

Studies on cognitive recovery after smoking cessation suggest that by 6 to 12 months of abstinence, brain function is much closer to that of someone who never smoked

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1 Introduction Atopic dermatitis (AD) is a prevalent chronic relapsing inflammatory skin disorder, clinically characterized by intense pruritus, eczematous lesions, and impaired skin barrier function, all of which significantly diminish patients quality of life ( Recent evidence suggests that pruritus in AD is not merely a unidirectional response of sensory neurons to external stimuli, but rather arises from complex neuroimmune interactions that sustain pathological signaling ( This review provides a comprehensive overview of the mast cellneuron axis in AD-related chronic pruritus, with emphasis on its structural basis, molecular pathways, and translational relevance for targeted therapeutic development

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