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cigarette manufacturers when they created the Tobacco Industry Research Committee (renamed the Council for Tobacco Research in 1964 following publication of the Surgeon Generals Report), which offered lucrative employment for scientists willing to cast doubt on the growing evidence of cigarette smoking as a major cause of death and disease

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Most smoking-related deaths arise from one of three types of disease: lung cancer, chronic obstructive pulmonary disease (COPD which incorporates emphysema and chronic bronchitis) and coronary heart disease (CHD)