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Furthermore, recent studies clearly show the harmful effects of WP smoking on human health, which include chronic bronchitis, emphysema, coronary artery disease, lung, gastric and esophageal cancers, and osteoporosis along with significant effects on embryogenesis 5,6

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In Parkinson's disease, nicotine may slow progression by inhibiting Sirtuin 6, thereby decreasing neuronal apoptosis and improving neuronal survival

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