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Instruct patients to inform their physician if they experience any signs or symptoms of liver injury including: loss of appetite, nausea, vomiting, fever, weakness, tiredness, right upper quadrant tenderness, itching, yellowing of the skin and eyes, light colored bowel movements or dark colored urine

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Many hazardous biproducts of e-vapour have been identified as cardiovascular toxins such as Acetaldehyde, acrolein and formaldehyde 2 along with heavy metal traces 3

TSPO radioligand binding correlates with the presence of activated microglia identified by immunohistochemistry in situ [12] and immunohistochemistry combined with autoradiography in brain tissue [9, 13], and is elevated in illnesses known to be associated with gliosis [14], though TSPO signal also arises from astroglia and endothelial cells [15]

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These contaminants can increase the risk of side effects