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SFNTC also sold and distributed other products associated with American Indian culture, such as Vignette Fact Cards containing stories of tribal leaders44 and a Book of Elders collection of interviews with elders across the USA and Canada,45 and distributed at least one mailing including a Pueblo tale of sacred tobacco.46 Emphasising tobacco as natural The final theme identified in the analysis was emphasising tobacco as natural and providing smokers a spiritual or sacred connection to the world, which appeared 22 times

Nicotine: medium

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This so-called ceiling effect might be due to a rapid but partial development of tolerance to the cardiovascular effects of nicotine (Benowitz, 1997)

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This Perspective proposes a mechanistic hypothesis to explain this paradox