retatrutide class can cause diarrhea Retatrutide is among a new of weight loss drugs being tested for their effectiveness Retatrutide: Benefits, Mechanism & Research

Pfizer and AstraZeneca recently agreed to lower the cost of prescription drugs for Medicaid after an executive order in May set a deadline for drugmakers to electively lower prices or face new limits on what the government will pay

For clinicians, understanding the mechanisms of GLP1 therapies is foundational

J Clin Endocrinol Metab 90(5):30093016

People on diet drugs need to prioritize protein sources and consider adding supplemental protein in the form of healthy shakes

Key contraindications include: Personal or family history of medullary thyroid cancer (MTC) or multiple endocrine neoplasia type 2 (MEN2) : Animal studies show a link to thyroid tumors, so these drugs are avoided to prevent potential risks

Foods that most reliably trigger GLP-1 include those high in soluble fiber (oats, lentils, chia seeds, Brussels sprouts), lean proteins (eggs, fatty fish, Greek yogurt, lean meats), and healthy fats (olive oil, avocados, nuts)