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Potential publication bias was assessed visually through funnel plot inspection and statistically using Eggers regression test

London: Guardian

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In 2006, a federal judge issued a damning 1,600-page opinion, detailing how these corporations marketed and sold their lethal products with zeal, with deception, with a single-minded focus on their financial success, and without regard for the human tragedy or social costs that success exacted. Worse still, Big Tobacco intentionally targets children, whom they refer to as replacement smokers. Industry documents reveal shocking admissions: The base of our business is the high school student, one memo stated

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