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Agostini et al
There's a problem, though

[74] [75] [76] Various news outlets and school districts have expressed the concern that these products have a high appeal to minors wanting to experiment with nicotine due to

The threat to the structures was, if not first identified, then at least made official when the National Trust for Historic Preservation gave tobacco barns "endangered" status in May of 2004
Pulmonary Fibrosis in COVID-19 Survivors: Predictive Factors and Risk Reduction Strategies Pulm Med, 2020

Nicotine, a well-known component of cigarette smoke, also alter metabolic pathways particularly by interfering with Organic Cation Transporters (OCTs) in vitro (Urakami et al., 1998
