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Those measures include: Fully reviewing e-cigarette products to ensure that they benefit public health before allowing them on the market Removing flavors from e-cigarettes, unless a manufacturer can show that a flavor contributes to completely switching from combustible products to e-cigarettes and that it does not appeal to youth Prohibiting internet and non-face-to-face sales of e-cigarettes These data also underscore the need for further FDA regulatory action to restrict the marketing and promotional efforts of e-cigarettes to younger audiences and establish mechanisms to reduce the sale of JUUL to minors