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Nicotine has additionally been found to induce vasoconstriction, which can affect the spinal cord, causing decreased perfusion, poor nutrition and potential medullary ischaemia (Baucher et al., 2021

The Impact of Novel Therapies on Quality-of-Life in Triple-Negative Breast Cancer: A Systematic Review of Clinical Trials

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Both sides presumably took that into account when hammering out this detail.

So, Chapter 1 is Live Animals, Chapter 41 is Raw Hides and Skins (other than Furskins) and Leather and Chapter 64 is Footwear

doi: 10.1016/j.fct.2018.04.035
