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Rights and permissions About this article Cite this article Bloomfield, M., Pepper, F., Egerton, A

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Canker sores Causes Mouth sores may be caused by irritation from: A sharp or broken tooth or poorly fitting dentures Biting your cheek, tongue, or lip Burning your mouth from hot food or drinks Braces Chewing tobacco Cold sores are caused by the herpes simplex virus

3.9 SNS and RAAS The SNS and the RAAS interact with each other in the form of a positive feedback loop: NE activates ANG II production by stimulating renin secretion, whereas circulating ANG II interacts with the SNS and potentiates NE release from sympathetic nerve terminals (Saxena, 1992