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One colonist wrote home to his parents in 1623 of the pervasiveness of disease in Virginia, the nature of the Country is such that it Causeth much sicknes, as the scurvie and the bloody flix, and divers other diseases, wch maketh the bodie very poore, and Weake, and when wee are sicke there is nothing to Comfort us. Early Settlement Soon after their arrival, the first English settlers constructed a fort to defend themselves