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No combustion means no carbon monoxide, no tar, and significantly fewer harmful byproducts than smoking

Nicotine Tob Res 22:264272 Kent JT, Mok G, Austin E (2024) Nicotine toxicity from repeat use of nicotine pouches

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These factors affect the overall health and addiction risks associated with smoking

Nicotine exerts its powerful effects primarily by binding to and activating nicotinic acetylcholine receptors (nAChRs) located throughout the central and peripheral nervous systems
