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Some of these, such as formaldehyde, acetaldehyde, and acrolein, are of concern due to their adverse impact on human health when inhaled at sufficient concentrations

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For instance, a pack-a day-smoker can expect to go through one ClearDraw2 cartridge or less per day

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Authors contributions DD, RF, MB, DR and JM designed, conducted and analysed the "Design and performance characteristics of an RTP cigarette" and "Split-tipping ventilation system" studies