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A better understanding of the nicotine-induced activation, desensitization, and upregulation of nAChRs has been considered to be the key to understanding tolerance to the effects of nicotine and nicotine dependence (De Biasi and Dani, 2010)
Int J Heal Sci 10:425435
Nunes DP, Lange MC, Zimmermann LM, Piovesan EJ, Scarinci IC
Additionally, they may advise someone to make changes to their diet and lifestyle
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